Hypertension is a growing global problem, which mostly affects the adults. It is a risk factor for death from stroke, myocardial infarction, congestive heart failure, ischemic heart disease, peripheral vascular disease, and progressive renal damage. These diseases are responsible for considerable morbidity and high mortality rate. Human essential hypertension (EH) is a complex and multifactorial trait influenced by environmental and genetic determinants. Early detection of genetic predisposition in hypertensive patients will enable prompt treatment and avoidance of complications. The use of SNPs in genetic disease detection is facilitated by the recent discovery of more than 4 million SNPs in the human genome that have the potential to be a rich source of genetic markers to establish genetic linkage and as indicators of disease. Such genetic research will open the new frontiers in diagnosis and treatment of diseases like hypertension.

Introduction: Dental caries and inflammatory periodontal diseases result from the accumulation of many different bacteria that form dental plaque, a naturally acquired bacterial biofilm that develops on the teeth. Periodontal diseases are one of the most prevalent oral diseases affecting more than 50% of Indian community. Materials and Method: A two months randomised controlled trial was conducted among ninety school children aged between 13 and 15 years, from a hostel located in Davangere city. The 90 study subjects who fulfilled inclusion and exclusion criteria were randomly divided into 3 groups namely Placebo, Chlorhexidine and Probiotic groups. Plaque scores were recorded at baseline (0 day), on 15 ^th day (after 14 days of intervention) and 3 weeks (after discontinuation of intervention). Statistical analysis was done using one way ANOVA and paired 't' test and P value less than 0.05 was considered statistically significant. Results: There was no statistically significant difference between groups at baseline. On 15 ^th day and after 3 weeks, plaque scores were significantly higher in placebo group compared to probiotic group. On 15 ^th day and after 3 weeks, plaque scores were higher in chlorhexidine group compared to probiotic group but difference was not statistically significant. Conclusion: Probiotic mouth rinse was more effective for inhibition of dental plaque accumulation after 14 days of intervention and also after 3 weeks of discontinuation of intervention.

Introduction: Zygomatic complex fractures or the tetrapod fractures are common to occur followed by the nasal bone fractures because of its prominent location. At the same time, it is difficult to obtain perfect reduction and contour postoperatively because of its complex involvement with four bones namely maxillary, temporal, orbital and greater wing of sphenoid bone. Various classifications have been put forward for better understanding and planning of treatment protocol. Aim: This study aims at comparing the following variables after reduction and fixation of fracture zygomatic complex; 1. Esthetics 2. Restoration of anatomical form 3. Occlusion 4. Function 5. Neurological deficits. Materials and Methods: Twenty patients were selected following a clinical and radiographic examination of fracture of the zygomatic complex. Reduction techniques used were Gillie's, Dingman's lateral eyebrow, and upper buccal sulcus approaches. Fixation was done at single-point or two-point or three-point protocol by transosseous wiring or miniplate osteosynthesis. Results: Among the twenty cases treated, all were males. Age distribution of the patients was between 20-60 years with a mean age of 39.5 years. There was facial asymmetry in four cases postoperatively and two among them did not follow postoperative instructions. Conclusions: Closed reduction namely Gillie's temporal approach was found to be the best reduction technique and the protocol of three point, miniplate fixation was effective in terms of stability and relapse.

Aggressive fibromatosis (AF) is identified to involve subcutaneous tissue, muscle, and neurovascular structures. Though the tumor is of bland histological features and low mitotic activity, it has a aggressive infiltrative growth pattern along tissue planes and invasion of adjacent tissue. Here we present a rare case report of a 19-year-old man with AF of the infratemporal region. Tumor growth was rapid and involved the infratemporal region. Biopsy was taken and in histological examination showed a tumor consisting of spindle-shaped fibroblast cells proliferating in fascicles within a collagenous stroma with rare atypia. Microscopically, a diagnosis of AF was rendered.