The susceptibility to various diseases is studied with association to genetic polymorphisms. Among these polymorphisms, single-nucleotide polymorphisms (SNPs) are very common throughout the genome. The recent advances in genetic assay techniques and increase in SNP databases are paving a way for investigation of susceptibility genes for periodontitis. This article attempts to review the role of SNP and its implications in periodontal disease and management.

A total of 56 anterior blepharitis cases including 22 cases of ulcerative blepharitis and 34 cases of seborrheic blepharitis were studied. The predominant age group of anterior blepharitis cases was above 40 years. With males affected more than females. In the order of decreasing frequency, the isolated bacteria from anterior blepharitis in order of decreasing frequency were Staphylococcus aureus 14 (25%), Staphylococcus epidermidis 14 (25%), similar Klebsiella species 10 (18%), viridans Streptococci five (9%), Pseudomonas aeruginosa five (9%), Proteus species four (7%), Enterobacter aerugenes three (5%), and Escherichia coli one (2%). The common isolates observed in both samples were S. aureus, S. epidermidis, and Proteus species. The Gram-positive cocci S. aureus were resistant to four antibiotics and viridans Streptococci were resistant to three antibiotics, whereas the Gram-negative bacteria were resistant to two antibiotics. Improper selection of antibiotics, inadequate dosing, and poor compliance to therapy may play an important role in increasing resistance. Identification of anterior blepharitis pathogens and performing antibiotic susceptibility test are important factors in reducing the resistance to therapy.

Ossifying fibroma is a benign, slow growing, and expansile lesion of the jaws. It is classified as one of the benign fibro-osseous lesions of the jaws. The juvenile ossifying fibroma (JOF) is commonly found in children and young adults. The juvenile variety of ossifying fibroma is more aggressive and requires a more extensive therapy because it might recur after curettage. It usually occurs in the mandibular premolar-molar area. The slow growth of the tumor may produce expansion and thinning of the buccal and lingual cortical plates. The treatment of the JOF is conservative surgical contouring either using curettage or enucleation. The lesion can be separated easily from the surrounding normal bone. Large ossifying fibroma requires surgical resection to reestablish normal facial symmetry. A long-term follow up is required for the lesion.

In the practice of fixed prosthodontics, certain situations like pier abutments, tilted abutments pose problems with rigid connectors. If rigid connectors are used in this situation, the pier abutment will act as a fulcrum because of physiologic tooth movement, arch position of the abutment, and the retentive capacity of the retainers. A nonrigid connector may be preferred in fabrication of fixed partial denture (FPD) with pier abutment. In this prosthesis, the movement of the nonrigid connector is enough to prevent the pier abutment from serving as a fulcrum. This clinical report describes rehabilitation of a patient with FPD with pier abutment using semi-precision attachment. The technique used is simple, economical, and feasible in an ordinary laboratory set up.